![]() sentinel lymph nodes were sent for frozen - section examination 192 of these. Validity of frozen section examination in comparison with permanent sections showed a sensitivity and specificity of 100%. Our study aims to evaluate the OSNA method in comparison with frozen section (FS) and definitive histological examination of the sentinel lymph node biopsy among early breast cancer patients considering disease-free survival (DFS) and overall survival (OS). Approximately 50 of sentinel lymph node operations are performed by each. all 10 cases (100%), the primary tumor size measured >2cm, (i.e: pT2). Nine of them (90%) were of ductal type, while only 1 case (10%) was of lobular type. Only 10 patients (30.3%) of the total cases were diagnosed as having POSITIVE SLNs by intraoperative frozen section examination, while 23 patients (69.7%) had NEGATIVE SLNs. Sentinel lymph node (SLN) biopsy has recently emerged as a substitute for axillary dissection in patients with clinically negative axillary nodes and can spare. Background: Sentinel lymph node biopsy (SLNB) is the standard approach for the axillary region in early breast cancer patients with clinically negative nodes. Results: The patients age was ranging from 32 to 79 years with a mean of 50.7 years and the highest proportion was ≥ 40 years (90%). Comparison of intraoperative frozen section analysis for sentinel lymph node biopsy during breast cancer surgery for invasive lobular carcinoma and invasive. and compared it with the permanent H&E sections, covering the period between Jan.2019 and Jan.2021 Materials and methods In this combined retrospective and prospective study, we reviewed the outcome for 33 female patients with breast cancer who underwent intraoperative SLN biopsy, at (Al-Shariqa laboratory) and (Ghazi Al-Hariri Hospital, Medical City) Baghdad, Iraq. To verify the accuracy of intraoperative frozen section examination for SLNs. Intraoperative sentinel lymph node (SLN) analysis by frozen section can determine whether or not ALND should be performed. To evaluate the current role of frozen section in identifying patients who could benefit from it.Ģ. Sentinel lymph node biopsy (SLNB) has been proposed as a less invasive alternative to axillary lymph node dissection (ALND) for axillary staging in early-stage breast cancer patients. Intraoperative frozen section of SLNs can detect metastatic disease, allowing immediate axillary dissection and avoiding the need for reoperation, at the same time it avoids unnecessary dissection of uninvolved LNs.ġ. Background Breast carcinoma is the most common malignancy in women worldwide.
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